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Archivos argentinos de pediatría
versão impressa ISSN 0325-0075versão On-line ISSN 1668-3501
Resumo
BOENTE, María del C; BIBAS BONET, Hilda e PRIMC, Norma B. Dermatopathy associated with levamisole-induced reversible posterior leukoencephalopathy. Arch. argent. pediatr. [online]. 2008, vol.106, n.1, pp.42-46. ISSN 0325-0075.
Levamisole is an antihelmintic drug that stimulates antibodies formation increasing both T response, and neutrophilic response, and quimiotaxis. It is used in dermatology for the treatment of plane warts, erythema multiforme, aphtous ulcers and, with prednisone, in lichen planus. With prolonged use this drug has been implicated in adverse dermatological reactions as lichenoid eruptions, ulcers and vasculitis. We present a 9-years old girl who developed a cutaneous eruption and a reverse leucoencephalopathy with a short treatment but high doses of the drug.