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Archivos argentinos de pediatría
versão impressa ISSN 0325-0075versão On-line ISSN 1668-3501
Resumo
PEREIRA-OSPINA, Rocío del P; BEJARANO-QUINTERO, Ana M; SUESCUN-VARGAS, José M e PINZON-SALAMANCA, Javier Y. Drug reaction with eosinophilia and systemic symptoms due to carbamazepine: Pediatric case. Arch. argent. pediatr. [online]. 2018, vol.116, n.3, pp.e433-e36. ISSN 0325-0075. http://dx.doi.org/10.5546/aap2018.e433.
Severe skin reactions include Stevens-Johnson Syndrome, toxic epidermal necrolysis and Drug reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome, which are uncommon in the pediatric population (incidence 1/1000-10 000 children), but they have bad prognosis. Drug-sensitive Syndrome with eosinophilia and systemic symptoms consists in rash, hematological abnormalities, lymphadenopathy and organ involvement. We report the case of a 12-year-old male patient who developed this pathology after initiating anticonvulsant therapy with carbamazepine. We consider that it is important to be aware of this disease and to include it among the differential diagnoses in patients with similar conditions because this syndrome is life-threatening.
Palavras-chave : DRESS syndrome; Drug hypersensitivity syndrome: Pediatrics; Carbamazepine.