Resumo

FRANCHINI, Gisela Raquel et al. Structural and functional analysis of soluble lipid binding proteins from parasitic helminths. Acta bioquím. clín. latinoam. [online]. 2013, vol.47, n.2, pp.377-384. ISSN 0325-2957.

Helminth parasites produce and secrete a great variety of lipid binding proteins (LBPs) that may participate in the acquisition of nutrients such as fatty acids and cholesterol from their host. It is also postulated that LBPs might interfere in the regulation of the host's immune response. Knowing more about the structure of these proteins as well as their interactions with ligands and membranes is important in order to understand the host-parasite interaction that they could mediate. On the other hand, these studies will contribute to obtain further knowledge about the mechanisms of helminth infection and the role that these proteins play in helminth biology. Moreover, this information would be useful to set new therapeutic and prevention measures for the diseases caused by these parasites.

Palavras-chave : Lipid binding proteins; Fatty aid binding protein; Parasites; Helminths; Nematodes; Cestodes; Fatty acid; Lipids.

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