Resumo

ANZIANI, O.S  e  FIEL, C.A. Resistencia a los antihelmínticos en nematodos que parasitan a los rumiantes en la Argentina. RIA. Rev. investig. agropecu. [online]. 2015, vol.41, n.1, pp.34-46. ISSN 1669-2314.

Anthelmintic resistance (AR) in nematodes of ruminants is a serious productive and health problem in the northern and central areas of Argentina. The use of anthelmintics has led not only to a significant increase in ruminant productivity but also a severe selection pressure on the parasite genome. Parasite resistance is particularly high in nematodes of small ruminants. Simultaneous resistance to two or more anthelmintics (imidazothiazoles, benzimidazoles, closantel and macrociclic lactones) has been repeatedly reported. In cattle nematodes exist also a rapid increase in AR, although documented cases of multiple resistance to broad-spectrum anthelmintics so far are not as numerous and imidazothiazoles still remain active. It is obvious that for sheep, goats and cattle, current management practices based solely on anthelmintics are no longer sustainable. Alternatives are required for the management of resistant populations and future monitoring programs to maintain animal productivity but also exert less selection pressure on parasites. Early diagnosis, populations in refuge, the possibility of selective and non-mass treatment, the exclusive use of anthelmintics under prescription and the eventual use of combinations of drugs are discussed in this review attempting a holistic view of the problem.

Palavras-chave : Small ruminants; Cattle; Argentina; Anthelmintic resistance.

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