Background:

Transcatheter aortic valve implantation (TAVI) has been shown to be beneficial in patients with intermediate risk; however, there is no overall analysis reporting TAVI results in our country.

Objectives:

To conduct a single-arm meta-analysis of local studies reporting 30-day outcomes after TAVI in intermediate risk patients in Argentina.

Methods:

A systematic review on TAVI was performed using controlled trials and observational studies identified in MEDLINE, Embase, SCOPUS and Cochrane to August 2019.

Results:

Among 59 articles identified through the database search, only 4 local observational studies reported 30-day mortality and complications after TAVI in moderate-risk patients according to the STS (Society of Thoracic Surgeons) score ranging between 4 and 7%. In 494 patients, 30-day mortality was 4.8%. Weighted pooled estimates of the studies were: stroke 2.7%, myocardial infarction 1.0%, need for a definitive pacemaker 24.8%, moderate or severe periprosthetic leakage 16.7%, and major bleeding 5.5%.

Conclusions:

The proven efficacy of TAVI is generating an expansion of its indication to patients with intermediate and low risk, However, this shift should be supported by local evidence of its benefit over traditional valve surgery. This single-arm meta-analysis of Argentine studies presents 30-day mortality and complications after TAVI in intermediate risk patients. The updated information of the local TAVI outcomes will serve as a standard in our settings.

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