Resumo

PEREZ DE ARENAZA, DIEGO et al. Imaging in Cardiac Amyloidosis. Rev. argent. cardiol. [online]. 2021, vol.89, n.3, pp.253-261.  Epub 01-Jun-2021. ISSN 1850-3748.  http://dx.doi.org/10.7775/rac.es.v89.i3.20394.

Cardiac amyloidosis is a systemic disorder caused by the extracellular deposition of fibrils of insoluble proteins that misfold and deposit in the myocardium. Patients with amyloidosis and cardiac involvement have higher mortality rate than those without cardiac involvement. The two most prevalent types are amyloidosis with cardiac involvement are light-chain amyloidosis (AL) due to immunoglobulin light chain deposition and transthyretin amyloidosis (ATTR) due to deposition of mutated or senile forms of the transthyretin (TTR) protein. The aim of this paper is to review the different modalities of cardiac imaging tests (echocardiography, cardiac magnetic resonance imaging, nuclear medicine images and computed tomography scan) that can determine the severity of cardiac involvement in patients with amyloidosis, the type of amyloidosis and its prognosis. Finally, a diagnostic algorithm is proposed to determine cardiac involvement in amyloidosis, tailored to the diagnostic tools locally available with a practical and clinical approach.

Palavras-chave : Amyloidosis/diagnostic imaging; Cardiomyopathies/diagnostic imaging; Echocardiography; Magnetic Resonance Imaging.

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