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Revista argentina de cardiología
versão On-line ISSN 1850-3748
Resumo
BOCIAN, JORGE L. et al. Prevalence of the Different Causes of Troponin Elevation in a Multicenter Registry in Bariloche. Link Between the Magnitude of Troponin Elevation and its Etiology. Rev. argent. cardiol. [online]. 2021, vol.89, n.5, pp.462-465. Epub 01-Out-2021. ISSN 1850-3748. http://dx.doi.org/10.7775/rac.es.v89.i5.20440.
Objectives:
To determine the prevalence of acute myocardial infarction (AMI) and other etiologies in patients with elevated troponin, to associate troponin values with the etiology, and to define the optimal cut-off point to differentiate AMI from other causes.
Methods:
All patients with elevated troponin who were hospitalized within 1 year and registered in the REGIBAR study were included. Magnitude was analyzed with the highest dose value/baseline value. The ROC curve and the Youden index were used to determine the optimal cut-off point.
Results:
A total of 150 cases were included (age: 66.3 ± 13.8 years, 71% male); 109 AMI (age: 71.1 years, 63.5% male), 18 (12%) with other cardiac causes, 15 (10%) with non-cardiac causes, and 8 (5.3%) with no evident etiology. The optimal cut-off point for troponin dose/baseline value to discriminate AMI was >3.15.
Conclusions:
A 73% of inpatients with elevated troponin were AMI cases (>3.15 times the cut-off point). Heart failure was the second most common cause of elevated troponin.
Palavras-chave : Troponin; Acute miocardial infarction; Heart failure.