Resumo

MOREYRA¹, Camila et al. Efecto de la cafeína sobre la presión arterial y parámetros de la rigidez vascular. Insuf. card. [online]. 2018, vol.13, n.2, pp.67-71. ISSN 1852-3862.

Introduction. Caffeine is one of the most consumed substances worldwide. Its physiological effects have been generated concerns about its potential harmful effects at the cardiovascular level. Objectives. To determine the effect of usual doses of caffeine (50mg) on hemodynamic variables assessed with the Mobil-O-GRAPH PWA in healthy subjects. To assess if smoking exacerbates the effect of coffee on these parameters. Materials and methods. Prospective study. We included healthy subjects between 18 and 55 years of age, of both sexes who had to be 12 hours free of cigarettes or substances with caffeine. Measurements of hemodynamic parameters were obtained with the Mobil-O-GRAPH PWA before and at 0, 30 and 60 minutes of the consumption of 140 mL of coffee with 50 mg of caffeine. It was evaluated if smoking exacerbates the effect of caffeine on these vascular parameters. Results. We included 27 patients of which 45% were male, with a mean age of 33 ± 9 years. The 29% of the patients were smokers. At 60 minutes of coffee intake, an increase of 3 mm Hg in mean arterial pressure (MAP) was observed, which was significant (p = 0.03). Compared to non smokers, smokers showed a more marked increase in MAP (9 mm Hg vs 2 mm Hg, p = 0.05). The other parameters were similar in both groups. Conclusion. In healthy subjects the intake of 50 mg of coffee increases the MAP by 3mmHg at 60 minutes and this effect is more marked in smokers.

Palavras-chave : Caffeine; Arterial stiffness; Mean arterial pressure.

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