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BAG. Journal of basic and applied genetics
versão On-line ISSN 1852-6233
Resumo
PETINO ZAPPALA, M.A e FANARA, J.J. Genetic architecture as an analysis tool of the genotype-phenotype map. BAG, J. basic appl. genet. [online]. 2018, vol.29, n.1, pp.25-36. ISSN 1852-6233.
Studying the relationship between genotype and phenotype is of great importance for genetics and life science studies in general. In contrast with the traditional view of this relationship as an invariant set of parameters, the current approach incorporates the concept of genetic architecture, a realistic and dynamic tool that allows to elucidate the genotype-phenotype map, which is now regarded as an evolving structure. From the complex relationships between the elements in the genotype-phenotype map several emergent properties arise that can explain different evolutionary phenomena. Moreover, some of these properties promote the accumulation of genetic variability in natural populations, which constitutes the substrate to evolutionary processes such as natural selection. The characterization and analysis of the genetic architecture of adaptive traits constitutes a powerful tool to understand the genetics underpinnings of evolution.
Palavras-chave : Plasticity; Canalization; Modularity; Cryptic genetic variability; Evolvability.