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Medicina (Buenos Aires)
versão impressa ISSN 0025-7680versão On-line ISSN 1669-9106
Resumo
CAMPOS-CASTELLO, Jaime. Role of generic antiepileptic drugs in the treatment of childhood epilepsy. Medicina (B. Aires) [online]. 2009, vol.69, n.1, suppl.1, pp.109-113. ISSN 0025-7680.
The use of generic instead of trade mark antiepileptic drugs raises the question of cost/benefit risks. The efficacy and side effects of the generic AED should be similar to the trade mark drugs. Otherwise, the substitution is not justified despite the benefits of reduced cost if efficacy or side effects are not similar in order to avoid possible recurrence of seizures with potential health hazard consequences and legal action. The purpose of this paper is to review the scientific medical literature to determine the efficacy and side effects of generic and trademark antiepileptic drugs.
Palavras-chave : Generic antiepileptic drugs; Cost [benefits]; Bioequivalence.